Description

4-(5-Nitropyridin-2-Yl)Benzoic Acid is a high-purity, multifunctional heterocyclic building block and intermediate of significant commercial interest. Its core value lies in its unique molecular architecture, which combines a benzoic acid moiety with a nitropyridine ring, making it a versatile synthon for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of advanced organic electronic materials and dyes.
• Chemical Biology: Utilized as a probe or linker molecule in biochemical assays and diagnostic development.
• Custom Synthesis: A fundamental building block for contract research organizations (CROs) and fine chemical suppliers for bespoke chemical synthesis projects.

Basic Information

Product Name	4-(5-Nitropyridin-2-Yl)Benzoic Acid
CAS No.	223127-49-9
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	2-(4-Carboxyphenyl)-5-nitropyridine; 5-Nitro-2-(4-carboxyphenyl)pyridine; 4-(5-Nitro-2-pyridinyl)benzoic acid; Benzoic acid, 4-(5-nitro-2-pyridinyl)-; [1,1'-Biphenyl]-4-carboxylic acid, 5'-nitro-2'-pyridyl analog
EINECS	Contact for details

Quality Control

Our 4-(5-Nitropyridin-2-Yl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.