Description

6-(4-Fluorophenyl)-Nicotinic Acid is a high-purity fluorinated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated aromatic ring and a carboxylic acid functional group, enabling precise modifications in complex chemical pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal-catalyzed cross-coupling reactions in fine chemical production.
• Material Science Research: Monomer or functionalizing agent for creating fluorinated polymers and advanced organic materials.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent tags or molecular probes for biological studies.

Basic Information

Product Name	6-(4-Fluorophenyl)-Nicotinic Acid
CAS No.	223127-24-0
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	6-(4-Fluorophenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-(4-fluorophenyl)-; 4-Fluoro-6-phenylnicotinic acid; 6-(p-Fluorophenyl)nicotinic acid; 6-(4-Fluorophenyl)-3-pyridinecarboxylic acid; 223127-24-0; 6-(4-Fluorophenyl)nicotinate
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.