Description

Methyl 4-(6-Hydroxyhex-1-Yn-1-Yl)Benzoate is a high-purity organic building block featuring a terminal alkyne and a protected benzoate ester group. This compound matters as a versatile synthetic intermediate, enabling the construction of complex molecular architectures through click chemistry and other coupling reactions. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those requiring alkyne-azide cycloaddition (click chemistry) for bioconjugation or library synthesis.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its alkyne functionality for structural diversification.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials and liquid crystal compounds with tailored properties.
• Polymer & Dendrimer Synthesis: Acts as a monomer or cross-linking agent for producing specialty polymers, dendrimers, and functionalized surfaces.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for labeling biomolecules in diagnostic and research applications.
• Academic & Contract Research: Essential reagent for organic synthesis projects in university laboratories and contract research organizations (CROs).

Basic Information

Product Name	Methyl 4-(6-Hydroxyhex-1-Yn-1-Yl)Benzoate
CAS No.	222983-64-4
Molecular Formula	C14H16O3
Molecular Weight	232.28 g/mol
Synonyms	Methyl 4-(6-Hydroxy-1-hexynyl)benzoate; Benzoic acid, 4-(6-hydroxy-1-hexyn-1-yl)-, methyl ester; 4-(6-Hydroxyhex-1-yn-1-yl)benzoic acid methyl ester; Methyl p-(6-hydroxyhex-1-ynyl)benzoate; 6-(4-(Methoxycarbonyl)phenyl)hex-5-yn-1-ol
EINECS	Contact for details

Quality Control

Our Methyl 4-(6-Hydroxyhex-1-Yn-1-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.