Description

2-[9H-Fluoren-9-Ylmethoxycarbonyl(Prop-2-Enyl)Amino]Acetic Acid is a specialized Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for introducing specific functional handles into peptide chains, enabling the creation of complex, modified biomolecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block for incorporating allyl-protected amino groups into peptide sequences.
• Orthogonal Protection Strategies: Enables complex multi-step synthesis where selective deprotection of specific functional groups is required.
• Bioconjugation and Linker Chemistry: Used to create peptide conjugates for drug delivery systems, antibody-drug conjugates (ADCs), and diagnostic probes.
• Chemical Biology Research: A valuable tool for studying protein-protein interactions and enzyme mechanisms through site-specific modification.
• Pharmaceutical Intermediate: Acts as a crucial intermediate in the synthesis of novel peptide-based active pharmaceutical ingredients (APIs).
• Material Science: Can be used in the synthesis of functionalized polymers and biomaterials with peptide motifs.

Basic Information

Product Name	2-[9H-Fluoren-9-Ylmethoxycarbonyl(Prop-2-Enyl)Amino]Acetic Acid
CAS No.	222725-35-1
Molecular Formula	C20H19NO4
Molecular Weight	337.37 g/mol
Synonyms	Fmoc-N(Alloc)-Gly-OH; N-Alloc-N-Fmoc-glycine; N-(9-Fluorenylmethoxycarbonyl)-N-(2-propenyloxycarbonyl)glycine; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl](2-propen-1-yloxycarbonyl)amino]acetic acid; Fmoc-Alloc-Gly; N-Alloc-N-Fmoc-Glycine; Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-[(2-propen-1-yloxy)carbonyl]-; (2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(allyloxycarbonyl)amino)acetic acid)
EINECS	Contact for details

Quality Control

Our 2-[9H-Fluoren-9-Ylmethoxycarbonyl(Prop-2-Enyl)Amino]Acetic Acid is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.