Description

cis-3-(Boc-Amino)Cyclohexanecarboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block for the construction of complex molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and bioactive compounds.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Peptidomimetics & Peptide Synthesis: Used to introduce constrained cyclohexyl scaffolds into peptide backbones, enhancing metabolic stability and bioavailability of peptide-based drug candidates.
• Combinatorial Chemistry & Library Synthesis: Employed in high-throughput screening libraries to generate diverse chemical space for hit identification in drug discovery programs.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Research: Utilized in the research and development of novel herbicides and fungicides with specific chiral requirements.
• Academic & Process Chemistry: Serves as a standard reagent in methodological development for asymmetric synthesis and scale-up process optimization.

Basic Information

Product Name	cis-3-(Boc-Amino)Cyclohexanecarboxylic Acid
CAS No.	222530-33-8
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	cis-3-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid; (1R,3S)-3-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid (if stereochemistry is specified); (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid; Boc-3-Amino-cyclohexanecarboxylic acid (cis); cis-3-(Boc-amino)cyclohexane-1-carboxylic acid; N-Boc-cis-3-aminocyclohexanecarboxylic acid; tert-Butyl (cis-3-carboxycyclohexyl)carbamate; Cyclohexanecarboxylic acid, 3-[(1,1-dimethylethoxy)carbonyl]amino]-, cis-
EINECS	Contact for details

Quality Control

Our cis-3-(Boc-Amino)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.