Description

Azetidine, 1-Benzoyl-3-Methylene- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique azetidine core fused with a benzoyl and exocyclic methylene group makes it a valuable precursor for constructing complex nitrogen-containing molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. Its utility lies in enabling the exploration of novel chemical space for drug discovery and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the synthesis of new herbicide and pesticide candidates, leveraging its nitrogen heterocycle for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Investigated as a monomer or building block for advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Azetidine, 1-Benzoyl-3-Methylene- (9Ci)
CAS No.	222527-63-1
Molecular Formula	C11H11NO
Molecular Weight	173.21 g/mol
Synonyms	1-Benzoyl-3-methylideneazetidine; 3-Methylene-1-benzoylazetidine; 1-Benzoyl-3-methyleneazetidine; Azetidine, 1-benzoyl-3-methylene-; 222527-63-1; 1-Benzoylazetidin-3-ylidene; 3-Methyleneazetidine-1-carboxylic acid phenyl ester
EINECS	Contact for details

Quality Control

Every batch of Azetidine, 1-Benzoyl-3-Methylene- (9Ci) is produced and handled under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profile. Our quality commitment ensures reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.