Description

(2S,2'S)-2-Amino-4-Methyl-Pentanoic Acid 6-(2-Amino-4-Methyl-Pentanoyloxy)-Hexyl Ester is a specialized, high-purity synthetic amino acid derivative designed for advanced research and development. This compound matters for its role as a critical building block in the synthesis of complex peptides and other bioactive molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and advanced material scientists working on novel drug candidates, targeted delivery systems, and sophisticated chemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation & Linker Chemistry: Used to create cleavable linkers or spacers in antibody-drug conjugates (ADCs) and other targeted drug delivery platforms.
• Proteomics Research: Serves as a specialized reagent or standard in mass spectrometry and other analytical techniques for studying protein structure and function.
• Chemical Biology: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and other molecular tools for probing biological pathways.
• Advanced Material Synthesis: A potential monomer or modifier for creating functionalized polymers with specific biological or chemical properties.

Basic Information

Product Name	(2S,2'S)-2-Amino-4-Methyl-Pentanoic Acid 6-(2-Amino-4-Methyl-Pentanoyloxy)-Hexyl Ester
CAS No.	221394-20-3
Molecular Formula	C18H36N2O4
Molecular Weight	344.50 g/mol
Synonyms	6-[(2S)-2-Amino-4-methylpentanoyl]oxyhexyl (2S)-2-amino-4-methylpentanoate; L-Leucine, 6-[(2S)-2-amino-4-methyl-1-oxopentyl]oxyhexyl ester; Bis(leucine) hexylene diester; Hexamethylene bis(L-leucinate); Amino acid-based diester; 221394-20-3; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (2S,2'S)-2-Amino-4-Methyl-Pentanoic Acid 6-(2-Amino-4-Methyl-Pentanoyloxy)-Hexyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.