Description

Oxiranecarboxylic Acid, 3-Methyl-, 1-Methylethyl Ester, (2R,3S)- (9Ci) is a high-purity, stereochemically defined chiral epoxide derivative. This compound serves as a critical chiral building block and intermediate in the synthesis of complex, biologically active molecules, offering precise control over stereochemistry in the final product. It is essential for research and development chemists in the pharmaceutical and agrochemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of protease inhibitors, antiviral agents, and other therapeutics where stereochemistry is crucial.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where the specific stereoisomer can significantly impact biological activity and environmental profile.
• Asymmetric Synthesis: Employed as a chiral electrophile or building block in stereoselective reactions, including nucleophilic ring-opening, to introduce chiral centers with high enantiomeric excess.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials that require specific three-dimensional architecture.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes to complex natural products.

Basic Information

Product Name	Oxiranecarboxylic Acid, 3-Methyl-, 1-Methylethyl Ester, (2R,3S)- (9Ci)
CAS No.	221203-39-0
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(2R,3S)-3-Methyloxiranecarboxylic Acid Isopropyl Ester; (-)-Isopropyl (2R,3S)-3-Methylglycidate; (2R,3S)-Isopropyl 3-Methylglycidate; (2R,3S)-3-Methylglycidic Acid Isopropyl Ester; Isopropyl (2R,3S)-(-)-3-Methylglycidate; (2R,3S)-3-Methyl-2-oxiranecarboxylic Acid 1-Methylethyl Ester; Chiral Isopropyl 3-Methylglycidate
EINECS	Contact for details

Quality Control

Our Oxiranecarboxylic Acid, 3-Methyl-, 1-Methylethyl Ester, (2R,3S)- (9Ci) is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay, enantiomeric excess (ee), and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its epoxide functionality and light-sensitive nature, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.