Description

2-Thiophenecarboxaldehyde, 3-Ethynyl- (9Ci) is a specialized heterocyclic building block that combines a thiophene aldehyde core with a reactive ethynyl substituent. This compound matters for its unique bifunctional reactivity, serving as a versatile precursor for constructing complex molecular architectures in advanced materials and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics industries for synthesizing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides with novel modes of action.
• Material Science & Organic Electronics: Serves as a crucial monomer or cross-linking agent in the synthesis of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized in click chemistry applications for bioconjugation and the labeling of biomolecules due to its terminal alkyne functionality.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Thiophenecarboxaldehyde, 3-Ethynyl- (9Ci)
CAS No.	221103-69-1
Molecular Formula	C7H4OS
Molecular Weight	136.17 g/mol
Synonyms	3-Ethynyl-2-thiophenecarboxaldehyde; 3-Ethynylthiophene-2-carbaldehyde; 2-Formyl-3-ethynylthiophene; 3-Ethynyl-2-formylthiophene; 3-Ethynylthiophene-2-carboxaldehyde; 3-Ethynylthiophene-2-aldehyde
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxaldehyde, 3-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.