Description

5-Chloro-2,3-Dihydro-1-Oxo-1H-Indene-2-Carbonitrile is a versatile and high-value indane-based building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a unique fused-ring scaffold for molecular diversification. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the design and production of new-generation herbicides and pesticides.
• Material Science Research: Used in the synthesis of organic semiconductors, ligands for catalysis, and other functional materials.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Chloro-2,3-Dihydro-1-Oxo-1H-Indene-2-Carbonitrile
CAS No.	220867-41-4
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	5-Chloro-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile; 5-Chloro-2-cyano-2,3-dihydro-1H-inden-1-one; 2,3-Dihydro-5-chloro-1-oxo-1H-indene-2-carbonitrile; 5-Chloro-2,3-dihydroinden-1-one-2-carbonitrile; 220867-41-4; 5-Chloro-1-indanone-2-carbonitrile; 5-Chloro-2-cyanoindan-1-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Dihydro-1-Oxo-1H-Indene-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.