Description

5-Isoxazolecarboxaldehyde,3-(Trifluoromethyl)-(9Ci) is a high-value trifluoromethylated heterocyclic building block, essential for introducing the isoxazole pharmacophore into complex molecular architectures. Its core value lies in enabling the synthesis of novel compounds with enhanced biological activity and metabolic stability, driven by the unique properties of the trifluoromethyl group. This advanced intermediate is critically needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in areas like kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in constructing active molecules for new-generation herbicides, fungicides, and insecticides, where the isoxazole ring contributes to efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology & Probe Development: Employed in creating molecular probes and labeled compounds for studying biological pathways and mechanisms of action.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Isoxazolecarboxaldehyde,3-(Trifluoromethyl)-(9Ci)
CAS No.	220780-62-1
Molecular Formula	C5H2F3NO2
Molecular Weight	165.07 g/mol
Synonyms	3-(Trifluoromethyl)isoxazole-5-carboxaldehyde; 3-(Trifluoromethyl)-1,2-oxazole-5-carbaldehyde; 5-Formyl-3-(trifluoromethyl)isoxazole; 3-Trifluoromethyl-5-isoxazolecarboxaldehyde; 220780-62-1; 3-Trifluoromethylisoxazole-5-carbaldehyde; 5-Carbaldehyde-3-trifluoromethylisoxazole
EINECS	Contact for details

Quality Control

Our 5-Isoxazolecarboxaldehyde,3-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.