Description

4-Amino-5,5,5-trifluoro-3-pentenoic acid ethyl ester is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl-substituted enamine structure, which is a versatile precursor for introducing fluorine atoms into complex molecules, thereby modifying their physical, chemical, and biological properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity and environmental stability.
• Advanced Material Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and specialty coatings with unique surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and exploring new fluorination reactions.
• Fine Chemical Manufacturing: Integrated into multi-step synthesis processes for producing high-value, complex fluorinated molecules.

Basic Information

Product Name	4-Amino-5,5,5-Trifluoro-3-Pentenoic Acid Ethyl Ester
CAS No.	220719-76-6
Molecular Formula	C7H10F3NO2
Molecular Weight	197.16 g/mol
Synonyms	Ethyl 4-Amino-5,5,5-trifluoro-3-pentenoate; 5,5,5-Trifluoro-4-aminopent-3-enoic Acid Ethyl Ester; 4-Amino-5,5,5-trifluoropent-3-enoic Acid Ethyl Ester; (E)-Ethyl 4-amino-5,5,5-trifluoropent-3-enoate; 3-Pentenoic acid, 4-amino-5,5,5-trifluoro-, ethyl ester; Ethyl (E)-4-amino-5,5,5-trifluoropent-3-enoate; 4-Amino-5,5,5-trifluoro-3-pentenoate ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-5,5,5-trifluoro-3-pentenoic acid ethyl ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.