Description

Indole-4-Boronic Acid is a high-purity boronic acid derivative that serves as a critical synthetic building block in modern organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those containing indole scaffolds for oncology and CNS disorders.
• Agrochemical Synthesis: Used to construct novel heterocyclic compounds with potential herbicidal or insecticidal activity.
• Material Science Research: Building block for creating organic electronic materials, such as OLED emitters and charge-transport layers.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and sensors for studying biological processes.
• Academic & Contract Research: Fundamental reagent for methodological development in cross-coupling chemistry and heterocycle functionalization.
• Scale-up Process Development: Serves as a starting material for optimizing synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Indole-4-Boronic Acid
CAS No.	220465-43-0
Molecular Formula	C8H8BNO2
Molecular Weight	160.97 g/mol
Synonyms	4-Indoleboronic Acid; 1H-Indole-4-boronic Acid; (1H-Indol-4-yl)boronic Acid; B-(1H-Indol-4-yl)boronic Acid; Indol-4-ylboronic Acid; 4-Boron-1H-indole; 220465-43-0; Boronic acid, B-(1H-indol-4-yl)-
EINECS	Contact for details

Quality Control

Our Indole-4-Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.