Description

(6-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is a high-value trifluoromethylated pyridine derivative, a key structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound is essential for research and development in medicinal chemistry, where it serves as a versatile building block for creating novel active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical, agrochemical, and advanced material scientists require this intermediate for its unique combination of aromatic stability and the lipophilicity and metabolic stability imparted by the trifluoromethyl group.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	(6-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol
CAS No.	220455-42-5
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	2-(Trifluoromethyl)-6-(hydroxymethyl)phenylpyridine; [6-[2-(Trifluoromethyl)phenyl]-3-pyridinyl]methanol; 3-Pyridinemethanol, 6-[2-(trifluoromethyl)phenyl]-; (6-(2-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol; α-(6-(2-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol
EINECS	Contact for details

Quality Control

Our (6-[2-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.