Description

Ethanone, 1-(3,4-Dihydro-2-Methoxy-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a dihydropyran moiety, making it a valuable fluorinated building block for advanced chemical synthesis. Its unique structure offers significant potential for modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing the trifluoromethyl group to improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorinated component can enhance activity and environmental persistence profiles.
• Material Science Research: Acts as a precursor for synthesizing fluorinated polymers or liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel fluorination methodologies.
• Chemical Biology Probe Development: Utilized to create labeled compounds or activity-based probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethanone, 1-(3,4-Dihydro-2-Methoxy-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci)
CAS No.	220370-51-4
Molecular Formula	C8H9F3O3
Molecular Weight	210.15 g/mol
Synonyms	1-(3,4-Dihydro-2-methoxy-2H-pyran-5-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(3,4-dihydro-2-methoxy-2H-pyran-5-yl)ethanone; 5-Acetyl-2-methoxy-3,4-dihydro-2H-pyran, 5-trifluoroacetyl derivative; 2-Methoxy-3,4-dihydro-2H-pyran-5-yl trifluoromethyl ketone; Trifluoroacetyl dihydropyran derivative; TFAP derivative (contextual); Fluorinated dihydropyran ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3,4-Dihydro-2-Methoxy-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.