Description

1-Pyrrolidinecarboxaldehyde, 3-Amino-4-(Hydroxymethyl)-2-Methyl-, (2S,3R,4R)- (9Ci) is a high-purity, stereochemically defined pyrrolidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring multiple functional groups, makes it an invaluable intermediate for constructing complex molecules with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Proline Analogue Synthesis: Integral for constructing modified peptide backbones and non-natural amino acids for biochemical studies.
• Academic and R&D Laboratories: Employed in methodological research for new synthetic routes and the study of stereoselective reactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	1-Pyrrolidinecarboxaldehyde, 3-Amino-4-(Hydroxymethyl)-2-Methyl-, (2S,3R,4R)- (9Ci)
CAS No.	220280-45-5
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(2S,3R,4R)-3-Amino-4-(hydroxymethyl)-2-methylpyrrolidine-1-carbaldehyde; (2S,3R,4R)-3-Amino-4-(hydroxymethyl)-2-methyl-1-pyrrolidinecarboxaldehyde; 3-Amino-4-(hydroxymethyl)-2-methylpyrrolidine-1-carbaldehyde (stereoisomer); Chiral Pyrrolidine Aldehyde Derivative; (2S,3R,4R)-Amino-hydroxymethyl-methyl-pyrrolidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1-Pyrrolidinecarboxaldehyde, 3-Amino-4-(Hydroxymethyl)-2-Methyl-, (2S,3R,4R)- (9Ci) is manufactured and tested under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.