Description

Furan, 3,4-Diethoxytetrahydro-2,5-Dimethoxy-, (3R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined tetrahydrofuran derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, oxygenated scaffold with defined stereochemistry, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially those targeting neurological and cardiovascular diseases.
• Agrochemical Research: Used in developing novel pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in transition metal catalysis.
• Natural Product Synthesis: Employed in the total synthesis of natural products containing tetrahydrofuran or related oxygen heterocycle motifs.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Furan, 3,4-Diethoxytetrahydro-2,5-Dimethoxy-, (3R,4S)-Rel- (9Ci)
CAS No.	220279-85-6
Molecular Formula	C10H20O5
Molecular Weight	220.26 g/mol
Synonyms	(3R,4S)-3,4-Diethoxytetrahydro-2,5-dimethoxyfuran; rel-(3R,4S)-3,4-Diethoxytetrahydro-2,5-dimethoxyfuran; Tetrahydro-2,5-dimethoxy-3,4-diethoxyfuran, (3R,4S)-rel-; 3,4-Diethoxytetrahydro-2,5-dimethoxyfuran (rel-(3R,4S)-form); 2,5-Dimethoxy-3,4-diethoxytetrahydrofuran; Chiral 3,4-diethoxytetrahydro-2,5-dimethoxyfuran
EINECS	Contact for details

Quality Control

Our Furan, 3,4-Diethoxytetrahydro-2,5-Dimethoxy-, (3R,4S)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be sensitive to moisture and strong acids/bases; handle and store under inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (rel-(3R,4S))
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.