Description

(S)-2,2'-Dimethoxy-1,1'-Binaphthyl-3,3'-Diyldiboronic Acid is a high-value, enantiomerically pure boronic acid derivative, serving as a sophisticated chiral building block and ligand precursor in advanced organic synthesis. Its core value lies in enabling the construction of complex, stereodefined molecular architectures, which is critical for developing pharmaceuticals and functional materials. This compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical development, and materials science who require high-purity chiral intermediates for asymmetric catalysis and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and cancer.
• Asymmetric Catalysis Ligand: Used to prepare chiral ligands for transition-metal catalyzed reactions, such as Suzuki-Miyaura cross-couplings, to create enantiomerically enriched compounds.
• Agrochemical Synthesis: Employed in the development of novel, stereoselective herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Serves as a building block for chiral organic frameworks (COFs), polymers, and liquid crystals with specific optical properties.
• Academic & Process Research: A vital tool for methodological development in organic chemistry and scaling up enantioselective synthetic routes.

Basic Information

Item	Details
Product Name	(S)-2,2'-Dimethoxy-1,1'-Binaphthyl-3,3'-Diyldiboronic Acid
CAS No.	220204-00-2
Molecular Formula	C24H20B2O6
Molecular Weight	425.84 g/mol
Synonyms	(S)-3,3'-Diborono-2,2'-dimethoxy-1,1'-binaphthyl; (S)-BINOL-3,3'-diboronic acid; (S)-2,2'-Dimethoxy-1,1'-binaphthyl-3,3'-bis(boronic acid); (S)-3,3'-Bis(boronic acid)-2,2'-dimethoxy-1,1'-binaphthyl; (S)-DM-BINOL-3,3'-diboronic acid; (S)-DMB-Binol-3,3'-diboronic Acid; (S)-DMB-BINOL-3,3'-Diboronic Acid; (S)-DMB-BINOL-3,3'-Bis(boronic acid)
EINECS	Contact for details

Quality Control

Our (S)-2,2'-Dimethoxy-1,1'-Binaphthyl-3,3'-Diyldiboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, assay, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and potentially air/moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.