Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-Acetyl-, (1R,2S,3R,4S)-Rel-(-)- is a high-purity, enantiomerically defined chiral building block with a complex, rigid bicyclic structure. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical ingredients and fine chemicals, where its stereochemistry is critical for biological activity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active compounds and catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring specific three-dimensional molecular architecture.
• Asymmetric Synthesis: Serves as a precursor or ligand in catalytic asymmetric reactions to create other enantiomerically pure compounds.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where the specific isomer can affect efficacy and environmental profile.
• Material Science: Potential building block for advanced polymers and functional materials that benefit from its rigid, fused-ring backbone.
• Academic & Industrial R&D: Employed in chemical research for methodology development and the exploration of new reaction pathways involving strained olefins and aldehydes.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-Acetyl-, (1R,2S,3R,4S)-Rel-(-)-
CAS No.	220191-57-1
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(1R,2S,3R,4S)-3-Acetylbicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; (-)-3-Acetylnorborn-5-ene-2-carboxaldehyde; rel-(1R,2S,3R,4S)-3-Acetylbicyclo[2.2.1]hept-5-ene-2-carbaldehyde; 3-Acetylnorborn-5-ene-2-carboxaldehyde, (-)-; Bicyclo[2.2.1]hept-5-ene-2-carboxaldehyde, 3-acetyl-, (1R,2S,3R,4S)-rel-(-)-; Norbornene derivative aldehyde
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including Chiral HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.