Description

3-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Aniline is a versatile organoboron building block featuring a protected boronic ester group and a reactive aniline moiety. This compound is essential for modern synthetic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the boronic ester group allows for the introduction of complex aromatic systems.
• Material Science: Serves as a monomer or functionalization agent in creating organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new catalytic processes and boron chemistry.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Proteolysis-Targeting Chimera (PROTAC) Development: Used as a linker component in the design of bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	3-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Aniline
CAS No.	220080-93-3
Molecular Formula	C11H16BNO2
Molecular Weight	205.06 g/mol
Synonyms	2-(3-Aminophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzenamine; 3-Aminophenylboronic acid, 5,5-dimethyl-1,3,2-dioxaborinane ester; 3-(Dimethylborinan-2-yl)aniline; 3-Boronoaniline N-protected; Aniline, 3-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-; MIDA Boronate Aniline Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and GC-MS to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are available upon request, providing full transparency and traceability for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.