Description

Butanal, 2-Hydroxy-2-Methyl-3-Oxo-, (2R)- (9Ci) is a high-purity, chiral α-hydroxy ketone derivative, a key building block in advanced organic synthesis. Its defined stereochemistry and reactive functional groups make it a critical intermediate for the production of complex, optically active molecules. This compound is essential for R&D and manufacturing in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Serves as a chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used as a precursor for chiral ligands, catalysts, and auxiliaries in stereoselective chemical reactions.
• Fine Chemical Production: A key starting material for manufacturing specialty chemicals, including fragrances, flavors, and advanced agrochemicals.
• Academic & Industrial Research: Employed in methodological development and scale-up studies for novel synthetic pathways.
• Bioconjugate Chemistry: Potential use in the development of labeled compounds and probes for biochemical research.

Basic Information

Product Name	Butanal, 2-Hydroxy-2-Methyl-3-Oxo-, (2R)- (9Ci)
CAS No.	219907-83-2
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(2R)-2-Hydroxy-2-methyl-3-oxobutanal; (R)-2-Hydroxy-2-methyl-3-oxobutanal; 2-Methyl-2-hydroxy-3-oxobutanal, (R)-; 3-Oxobutan-2-ol, 2-methyl-, (2R)-; Butanal, 2-hydroxy-2-methyl-3-oxo-, (R)-; (R)-2-Hydroxy-2-methyl-3-oxobutyraldehyde; A chiral α-hydroxy β-keto aldehyde.
EINECS	Contact for details

Quality Control

Our Butanal, 2-Hydroxy-2-Methyl-3-Oxo-, (2R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.