Description

1-Bromo-3-Chloro-5-Nitrobenzene is a high-purity halogenated nitroaromatic compound serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitro and halogen groups confer specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and other colored compounds.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination to form biaryl structures.
• Organic Synthesis Reagent: Employed in nucleophilic aromatic substitution and reduction reactions to introduce amino or other functional groups.

Basic Information

Product Name	1-Bromo-3-Chloro-5-Nitrobenzene
CAS No.	219817-43-3
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	3-Chloro-5-nitro-1-bromobenzene; 3-Chloro-5-nitrobenzyl bromide; 1-Bromo-3-chloro-5-nitro-benzene; Benzene, 1-bromo-3-chloro-5-nitro-; 5-Nitro-1-bromo-3-chlorobenzene; 3-Chloro-5-nitrobenzylbromide; 3-Chloro-5-nitrophenyl bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.