Description

(2S,4S,5R)-2-Hydroxymethyl-5-Ethylquinuclidine is a high-purity, stereochemically defined chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemistry is critical. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, including potential candidates for neurological and cardiovascular applications.
• Asymmetric Catalysis Ligand Precursor: Serves as a foundational structure for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring the quinuclidine scaffold.
• Agrochemical Research: Used as an intermediate in the development of new, stereospecific pesticides and herbicides.
• Academic & Process Chemistry: A valuable tool for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(2S,4S,5R)-2-Hydroxymethyl-5-Ethylquinuclidine
CAS No.	219794-79-3
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	5-Ethyl-2-(hydroxymethyl)quinuclidine; (2S,4S,5R)-5-Ethyl-2-(hydroxymethyl)quinuclidine; 2-(Hydroxymethyl)-5-ethylquinuclidine; (2S,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine; Quinuclidine, 2-(hydroxymethyl)-5-ethyl-, (2S,4S,5R)-; Chiral Quinuclidine Derivative; 5-Ethylquinuclidine-2-methanol
EINECS	Contact for details

Quality Control

Our (2S,4S,5R)-2-Hydroxymethyl-5-Ethylquinuclidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.