Description

2-Chloro-1-Iodo-4-Methoxybenzene is a halogenated anisole derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on an activated aromatic ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents where its halogen atoms enable further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, leveraging the reactive iodo and chloro groups for selective bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex dyes and organic pigments.

Basic Information

Product Name	2-Chloro-1-Iodo-4-Methoxybenzene
CAS No.	219735-98-5
Molecular Formula	C7H6ClIO
Molecular Weight	284.48 g/mol
Synonyms	1-Chloro-2-iodo-4-methoxybenzene; 4-Methoxy-2-chloroiodobenzene; 2-Chloro-4-methoxyiodobenzene; 2-Chloro-4-methoxyphenyl iodide; 1-Iodo-2-chloro-4-methoxybenzene; 2-Chloro-1-iodo-4-methoxybenzene; (2-Chloro-4-methoxyphenyl)iodane
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Iodo-4-Methoxybenzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.