Description

3-(4-Bromo-2-Thienyl)-1-(4-Chloro-3-Methylphenyl)Prop-2-En-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its distinct thiophene and chalcone-based molecular architecture. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable bromo and chloro substituents.
• Organic Synthesis: Acts as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) facilitated by the bromothienyl moiety.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition or receptor binding interactions where the chalcone scaffold is relevant.
• Material Science Precursor: Investigated for the development of organic electronic materials, leveraging the conjugated system of the chalcone and thiophene units.

Basic Information

Product Name	3-(4-Bromo-2-Thienyl)-1-(4-Chloro-3-Methylphenyl)Prop-2-En-1-One
CAS No.	219619-24-6
Molecular Formula	C14H10BrClOS
Molecular Weight	341.65 g/mol
Synonyms	1-(4-Chloro-3-methylphenyl)-3-(4-bromo-2-thienyl)-2-propen-1-one; (E)-3-(4-Bromothiophen-2-yl)-1-(4-chloro-3-methylphenyl)prop-2-en-1-one; 4'-Chloro-3'-methylchalcone-4-bromo derivative; 219619-24-6; 3-(4-Bromo-2-thienyl)-1-(4-chloro-3-methylphenyl)-2-propen-1-one
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-2-Thienyl)-1-(4-Chloro-3-Methylphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.