Description

n-(3-Chloro-4-Fluoro-Phenyl)-2-Cyano-Acetamide is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the phenyl ring along with a cyanoacetamide moiety, makes it a critical building block for the development of complex molecules. This compound is essential for research and manufacturing chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aniline derivative.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in OLED displays and lighting due to its electron-deficient aromatic system.
• Liquid Crystal Intermediate: Employed in the production of fluorinated liquid crystals for high-performance displays.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and pigments, where the cyano and amide groups facilitate chromophore formation.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	n-(3-Chloro-4-Fluoro-Phenyl)-2-Cyano-Acetamide
CAS No.	219529-31-4
Molecular Formula	C9H6ClFN2O
Molecular Weight	212.61 g/mol
Synonyms	2-Cyano-N-(3-chloro-4-fluorophenyl)acetamide; (3-Chloro-4-fluorophenyl)carbamoylacetonitrile; N-(3-Chloro-4-fluorophenyl)-2-cyanoacetamide; Acetamide, 2-cyano-N-(3-chloro-4-fluorophenyl)-; 2-Cyanoacetic acid (3-chloro-4-fluoroanilide); 3-Chloro-4-fluoro-2-cyanoacetanilide
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-4-Fluoro-Phenyl)-2-Cyano-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.