Description

(Z)-1-Ethoxyethene-2-Boronic Acid Pinacol Ester CAS NO 219489-07-3 is a high-value, stereodefined vinyl boronic ester building block essential for modern cross-coupling chemistry. Its core value lies in enabling the precise and efficient introduction of a functionalized ethenyl group into complex molecular architectures, a critical step in pharmaceutical and advanced materials synthesis. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing key intermediates in drug discovery and fine chemical production.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key electrophile for forming carbon-carbon bonds with aryl/vinyl halides, enabling the synthesis of complex styrene and diene derivatives.
• Pharmaceutical Intermediate Synthesis: For constructing chiral or substituted olefin motifs present in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Active Ingredient Development: In the synthesis of novel herbicides, fungicides, and insecticides that require specific olefinic components.
• Material Science & OLED Precursors: Building block for creating conjugated organic molecules used in organic light-emitting diodes (OLEDs) and electronic materials.
• Ligand and Catalyst Synthesis: For the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology & Probe Development: Incorporation into molecular probes and bioconjugates for studying biological processes.

Basic Information

Product Name	(Z)-1-Ethoxyethene-2-Boronic Acid Pinacol Ester
CAS No.	219489-07-3
Molecular Formula	C10H19BO3
Molecular Weight	198.07 g/mol
Synonyms	(Z)-1-Ethoxyvinylboronic Acid Pinacol Ester; (Z)-1-Ethoxyethenylboronic Acid Pinacol Ester; (Z)-1-Ethoxyvinyl-2-boronic Acid Pinacol Ester; (Z)-1-Ethoxyethene-2-boronic Acid Pinacol Ester; (Z)-1-Ethoxyvinyl-2-Bpin; (Z)-1-Ethoxyvinylboronate Pinacol Ester; (Z)-2-(1-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (Z)-1-Ethoxyethenyl-2-Bpin
EINECS	Contact for details

Quality Control

Our (Z)-1-Ethoxyethene-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive cross-coupling applications. Each lot is analyzed by NMR (¹H, ¹³C, ¹¹B) and HPLC/GC to confirm chemical identity, isomeric purity (Z-configuration), and assay. Certificates of Analysis (COA) with full analytical data are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. The material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Isomeric Purity (Z-Isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.