Description

3-Methyl-2-Buten-2-Ylboronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a protected boronic ester derivative. This compound is a critical building block in modern synthetic chemistry, valued for its stability and reactivity in cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and organoboron compounds, essential for synthesizing complex organic molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing the prenyl or isopentenyl moiety.
• Agrochemical Product Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific branched-chain structures.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating activity-based probes for enzyme studies.
• Process Chemistry & Scale-Up: Provides a stable, handleable alternative to more sensitive boronic acids for large-scale manufacturing processes.

Basic Information

Product Name	3-Methyl-2-Buten-2-Ylboronic Acid Pinacol Ester
CAS No.	219488-99-0
Molecular Formula	C11H21BO2
Molecular Weight	196.10 g/mol
Synonyms	2-(3-Methylbut-2-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methyl-2-buten-2-ylboronic acid pinacol ester; Prenylboronic Acid Pinacol Ester; (3-Methylbut-2-en-2-yl)boronic acid pinacol ester; 2-(3-Methyl-2-buten-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Isopentenylboronic Acid Pinacol Ester; 219488-99-0
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-Buten-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistency and reliability for your sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.