Description

Ethanone,1-(2-Fluorophenyl)-2-Hydroxy-(9Ci) is a fluorinated aromatic ketone derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both a ketone and a hydroxyl group on an aromatic ring substituted with fluorine, makes it a critical intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its tunable electronic properties.
• Custom Synthesis and Contract Manufacturing: A crucial building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in university and institutional research for methodological studies and exploring new chemical reactions involving fluorinated compounds.

Basic Information

Product Name	Ethanone,1-(2-Fluorophenyl)-2-Hydroxy-(9Ci)
CAS No.	218771-68-7
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(2-Fluorophenyl)-2-hydroxyethanone; 2'-Fluoro-2-hydroxyacetophenone; 2-Hydroxy-1-(2-fluorophenyl)ethanone; 2-Hydroxy-2'-fluoroacetophenone; α-Hydroxy-2-fluoroacetophenone; 2-Fluoro-α-hydroxyacetophenone; NSC 405124; 2-Fluorophenacyl alcohol
EINECS	Contact for details

Quality Control

Every batch of Ethanone,1-(2-Fluorophenyl)-2-Hydroxy-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality commitment supports compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.