Description

Olean-9(11)-En-28-Oic Acid, 3,12-Dioxo-, Methyl Ester (9Ci) is a high-purity, semi-synthetic triterpenoid derivative of oleanolic acid, a compound of significant interest in pharmaceutical and biochemical research. This specific methyl ester derivative is valued for its enhanced bioavailability and stability compared to the parent acid, making it a crucial advanced intermediate. It is primarily sought by research institutions and pharmaceutical developers working on novel therapeutic agents, particularly in the fields of metabolic disease, inflammation, and oncology.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel semi-synthetic triterpenoid drugs and prodrugs targeting inflammation and cancer.
• Biochemical Research: Used as a reference standard and active compound in studies investigating the structure-activity relationships (SAR) of pentacyclic triterpenoids.
• Metabolic Pathway Studies: Employed in preclinical research to explore the modulation of metabolic enzymes and signaling pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for the development of new chemical entities with improved pharmacokinetic properties.
• Reference Material: Utilized in analytical laboratories for method development and quality control of related triterpenoid compounds.

Basic Information

Product Name	Olean-9(11)-En-28-Oic Acid, 3,12-Dioxo-, Methyl Ester (9Ci)
CAS No.	218600-50-1
Molecular Formula	C₃₁H₄₄O₅
Molecular Weight	496.68 g/mol
Synonyms	Methyl 3,12-dioxoolean-9(11)-en-28-oate; 3,12-Dioxoolean-9(11)-en-28-oic Acid Methyl Ester; Olean-9(11)-en-28-oic acid, 3,12-dioxo-, methyl ester; Methyl 3,12-dioxo-olean-9(11)-en-28-oate; 3,12-Diketone derivative of methyl oleanolate; Triterpenoid methyl ester derivative; CDDO-Methyl Ester (common research abbreviation); 9(11)-Dehydro derivative of methyl oleanonate
EINECS	Contact for details

Quality Control

Our Olean-9(11)-En-28-Oic Acid, 3,12-Dioxo-, Methyl Ester (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade chemicals, and specifications can be aligned with customer-specific requirements for advanced development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.