Description

(-)-N,N'-(1R,2R)-1,2-Diaminocyclohexanediylbis(2-Pyridinecarboxamide) is a high-purity, chiral diamine derivative that serves as a sophisticated ligand and building block in advanced chemical synthesis. Its rigid, chelating structure is critical for creating highly selective catalysts and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise stereochemical control in their processes.

Application

• Asymmetric Catalysis: A key chiral ligand for transition metal catalysts used in enantioselective hydrogenation, oxidation, and C-C bond-forming reactions.
• Pharmaceutical Intermediates: A crucial building block in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex molecules.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: A precursor for chiral polymers, metal-organic frameworks (MOFs), and other functional materials with specific optical or catalytic properties.
• Chemical Research: A valuable tool for academic and industrial R&D in organometallic chemistry and stereochemistry studies.
• Ligand for Metal Complexation: Forms stable complexes with various metals for applications in sensing, separation, and catalysis.

Basic Information

Product Name	(-)-N,N'-(1R,2R)-1,2-Diaminocyclohexanediylbis(2-Pyridinecarboxamide)
CAS No.	218290-24-5
Molecular Formula	C₁₈H₂₂N₆O₂
Molecular Weight	354.41 g/mol
Synonyms	(1R,2R)-(-)-1,2-Diaminocyclohexane-N,N'-bis(2-pyridinecarboxamide); (R,R)-(-)-1,2-Diaminocyclohexane-N,N'-di-2-pyridinecarboxamide; (R,R)-DACH-Pyridine; (R,R)-DACH-Py; Jacobsen Ligand Derivative; Chiral Pyridine Diamide Ligand; (-)-Cyclohexane-1,2-diamine N,N'-bis(2-pyridinylcarbonyl) derivative; (1R,2R)-N,N'-Bis(2-pyridinylcarbonyl)-1,2-cyclohexanediamine
EINECS	Contact for details

Quality Control

Our (-)-N,N'-(1R,2R)-1,2-Diaminocyclohexanediylbis(2-Pyridinecarboxamide) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. Our quality commitment aligns with the standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.