Description

4-Bromo-2-Methyl-1,3-Benzoxazole is a versatile halogenated benzoxazole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine substituent, which enables efficient cross-coupling reactions and functional group transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the benzoxazole core's bioactivity.
• Material Science Research: Serves as a precursor for creating functional organic materials, such as ligands for catalysts or monomers for specialty polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Preparation: Acts as a starting material for the synthesis of novel nitrogen-oxygen donor ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-2-Methyl-1,3-Benzoxazole
CAS No.	217326-69-7
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	4-Bromo-2-methylbenzoxazole; 2-Methyl-4-bromobenzoxazole; 4-Bromo-2-methyl-1,3-benzoxazole; Benzoxazole, 4-bromo-2-methyl-; 217326-69-7; 4-Bromo-2-methyl-benzooxazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-1,3-Benzoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.