Description

1-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]Ethan-1-One is a high-value, multi-functional organic intermediate characterized by its unique thiophene and trifluoromethylphenyl hybrid structure. This compound matters for its role as a critical building block in advanced synthesis, offering a versatile scaffold for introducing specific aromatic and fluorinated motifs into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers, organic semiconductors, and liquid crystalline materials.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a source of the phenyl-trifluoromethyl-thienyl moiety for synthesizing other complex fluorinated organic molecules.

Basic Information

Product Name	1-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]Ethan-1-One
CAS No.	217184-77-5
Molecular Formula	C13H9F3OS
Molecular Weight	270.27 g/mol
Synonyms	1-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]ethanone; 2-Acetyl-5-phenyl-4-(trifluoromethyl)thiophene; 2-Acetyl-4-phenyl-5-(trifluoromethyl)thiophene; 4-Phenyl-5-(trifluoromethyl)thiophene-2-yl methyl ketone; Ethanone, 1-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-; 217184-77-5; CAS 217184-77-5
EINECS	Contact for details

Quality Control

Our 1-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]Ethan-1-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.