Description

R-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde is a chiral binaphthyl derivative, a sophisticated organic building block prized for its axial chirality and functional group versatility. This compound matters as a key intermediate in the synthesis of advanced chiral ligands, catalysts, and pharmaceuticals, where its precise stereochemistry is critical for inducing enantioselectivity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel asymmetric synthesis routes.

Application

• Chiral Ligand Synthesis: A crucial precursor for constructing complex phosphine, phosphoramidite, and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Asymmetric Catalyst Development: Serves as a core scaffold for developing novel organocatalysts and transition metal catalysts for enantioselective C-C and C-X bond formation.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) that require a binaphthyl-based chiral center.
• Material Science Research: Employed in the synthesis of chiral organic materials, such as liquid crystals and polymers with specific optical properties.
• Agrochemical Synthesis: Acts as an intermediate for creating chiral active ingredients in herbicides and pesticides.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis and for scaling up enantioselective processes.

Basic Information

Product Name	R-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde
CAS No.	216978-80-2
Molecular Formula	C26H24O5
Molecular Weight	416.47 g/mol
Synonyms	(R)-3-Formyl-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL-Derived Dialdehyde; (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene-3-carbaldehyde; (R)-3-Carbaldehyde-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; R-BINOL MOM-protected aldehyde; (R)-BINOL-3-CHO (MOM-protected); (R)-2,2'-Di(methoxymethoxy)-1,1'-binaphthyl-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our R-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and purity assessment. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.