Description

Cyclopropanecarboxylic Acid, 2-Fluoro-, Propyl Ester, (1R,2R)-Rel- (9Ci) is a high-value, stereochemically defined fluorinated cyclopropane derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active ingredients, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated active ingredients for crop protection products, leveraging the fluorine atom's ability to influence biological activity and environmental persistence.
• Methodology Development: Serves as a model substrate in organic chemistry research for developing new asymmetric synthesis and fluorination methodologies.
• Ligand and Catalyst Precursor: Can be utilized in the synthesis of specialized chiral ligands or organocatalysts for enantioselective transformations.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers with unique properties derived from the strained cyclopropane ring and fluorine content.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-, Propyl Ester, (1R,2R)-Rel- (9Ci)
CAS No.	216872-00-3
Molecular Formula	C7H11FO2
Molecular Weight	146.16 g/mol
Synonyms	(1R,2R)-rel-2-Fluorocyclopropanecarboxylic Acid Propyl Ester; Propyl (1R,2R)-rel-2-Fluorocyclopropanecarboxylate; 2-Fluorocyclopropanecarboxylic Acid Propyl Ester, (1R,2R)-rel-; Fluorinated Cyclopropane Propyl Ester; Chiral Fluorocyclopropane Ester; (rel)-(1R,2R)-2-Fluorocyclopropanecarboxylic Acid Propyl Ester
EINECS	Contact for details

Quality Control

Every batch of our Cyclopropanecarboxylic Acid, 2-Fluoro-, Propyl Ester, (1R,2R)-Rel- (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including chiral purity (enantiomeric excess) and assay by HPLC, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (1R,2R)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.