Description

α-Bromo-4-(1-Pyrrolidino)Acetophenone is a specialized brominated ketone derivative featuring a pyrrolidine substituent, serving as a valuable synthetic intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmacologically active molecules and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for building novel heterocyclic compounds and as a key precursor in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators requiring specific heterocyclic motifs.
• Material Science Precursor: Employed in the creation of organic semiconductors, ligands for catalysis, or photoactive materials due to its electron-donating pyrrolidino group.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes and tools used in biochemical and cellular studies.
• Academic & R&D Laboratories: Utilized in methodological development and discovery chemistry for constructing complex, nitrogen-containing heterocycles.

Basic Information

Product Name	α-Bromo-4-(1-Pyrrolidino)Acetophenone
CAS No.	216144-18-2
Molecular Formula	C₁₂H₁₄BrNO
Molecular Weight	268.15 g/mol
Synonyms	2-Bromo-1-[4-(1-pyrrolidinyl)phenyl]ethanone; 2-Bromo-1-[4-(pyrrolidin-1-yl)phenyl]ethan-1-one; 4-Pyrrolidino-α-bromoacetophenone; 1-(4-Pyrrolidin-1-ylphenyl)-2-bromoethanone; α-Bromo-4-pyrrolidinoacetophenone; p-Pyrrolidino-α-bromoacetophenone; 216144-18-2; Bromo(4-pyrrolidin-1-ylphenyl)methanone
EINECS	Contact for details

Quality Control

Our α-Bromo-4-(1-Pyrrolidino)Acetophenone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.