Description

2-(4-Nitrophenyl)Ethenylboronic Acid is a specialized boronic acid derivative featuring a conjugated nitro-substituted ethenyl linker, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the nitro-substituted aromatic system offers a handle for further chemical transformations. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those containing biphenyl or extended conjugated systems via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific aromatic and olefinic components.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its electron-withdrawing nitro group and planar structure.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and sensors that target biological systems, leveraging the boronic acid's affinity for diols.
• Ligand Synthesis: Acts as a precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Employed in methodological studies and scale-up processes for new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-(4-Nitrophenyl)Ethenylboronic Acid
CAS No.	216019-32-8
Molecular Formula	C8H8BNO4
Molecular Weight	193.97 g/mol
Synonyms	2-(4-Nitrophenyl)vinylboronic acid; (2-(4-Nitrophenyl)ethenyl)boronic acid; 4-Nitrostyrylboronic acid; (E)-2-(4-Nitrophenyl)ethenylboronic acid; 4-Nitro-trans-styrylboronic acid; p-Nitrostyrylboronic acid; B-(2-(4-Nitrophenyl)vinyl)boronic acid; 216019-32-8
EINECS	Contact for details

Quality Control

Our 2-(4-Nitrophenyl)Ethenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.