Description

2,4-Dideoxy-6-o-(Phenylmethyl)-L-Threo-Hexonic Acid tert-Butyl Ester is a sophisticated chiral building block and protected sugar derivative of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex bioactive molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and organizations engaged in the synthesis of nucleoside analogs, antiviral agents, and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel antiviral and anticancer drug candidates.
• Nucleoside Analog Synthesis: Serves as a protected sugar moiety in the construction of modified nucleosides for medicinal chemistry.
• Carbohydrate Chemistry: Used in the synthesis of complex oligosaccharides, glycoconjugates, and other biologically active carbohydrate derivatives.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable tool for studying glycosylation reactions, stereoselective synthesis, and reaction mechanisms.
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	2,4-Dideoxy-6-o-(Phenylmethyl)-L-Threo-Hexonic Acid tert-Butyl Ester
CAS No.	215876-09-8
Molecular Formula	C₁₇H₂₄O₅
Molecular Weight	308.37 g/mol
Synonyms	tert-Butyl 2,4-dideoxy-6-O-benzyl-L-threo-hexonate; L-Threo-Hexonic acid, 2,4-dideoxy-6-O-(phenylmethyl)-, 1,1-dimethylethyl ester; 6-O-Benzyl-2,4-dideoxy-L-threo-hexonic acid tert-butyl ester; 2,4-Dideoxy-6-O-benzyl-L-threo-hexonic acid tert-butyl ester; Benzyl-protected L-threo-hexonate derivative; Chiral tert-butyl ester sugar intermediate
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard offering for this advanced intermediate typically meets a purity specification of ≥95% (by HPLC), with specifications for chiral purity and key impurities available. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profile is provided with each shipment. We support custom synthesis projects with tailored purity grades and analytical documentation to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.