Description

2-(4-Bromo-2-Methylphenyl)Acetonitrile is a versatile brominated aromatic nitrile intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bromine atom for further functionalization.
• Liquid Crystal Materials: Serves as a building block for mesogenic compounds used in display technologies due to its rigid aromatic core and modifiable functional groups.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions like Suzuki, Heck, and Sonogashira couplings.
• Chemical Research & Development: A valuable reagent for academic and industrial research in exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Bromo-2-Methylphenyl)Acetonitrile
CAS No.	215800-05-8
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	(4-Bromo-2-methylphenyl)acetonitrile; 2-Methyl-4-bromobenzyl cyanide; 4'-Bromo-2'-methylphenylacetonitrile; 2-(4-Bromo-2-methylphenyl)ethanenitrile; α-Cyano-4-bromo-2-methyltoluene; p-Bromo-o-tolylacetonitrile; 4-Bromo-2-methylbenzyl cyanide; 2-Methyl-4-bromophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Methylphenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed to minimize exposure to moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.