Description

Palladium, [(1S)-[1,1''-Binaphthalene]-2,2''-Diylbis[Bis(4-Methylphenyl)Phosphine-.Kappa.P]]Dichloro-, (Sp-4-2)- is a highly specialized, chiral palladium complex widely recognized as a premier catalyst in asymmetric synthesis. Its value lies in its ability to facilitate critical carbon-carbon and carbon-heteroatom bond-forming reactions with exceptional enantioselectivity and yield. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Cross-Coupling Reactions: A key catalyst for enantioselective Suzuki-Miyaura, Negishi, and Buchwald-Hartwig amination reactions.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Chemical Production: Enables the creation of high-value chiral building blocks and ligands.
• Academic and Industrial R&D: A vital tool for methodological development in organic synthesis and catalysis research.
• Material Science: Potential applications in the synthesis of chiral polymers and advanced functional materials.

Basic Information

Product Name	Palladium, [(1S)-[1,1''-Binaphthalene]-2,2''-Diylbis[Bis(4-Methylphenyl)Phosphine-.Kappa.P]]Dichloro-, (Sp-4-2)-
CAS No.	215597-19-6
Molecular Formula	C54H44Cl2P2Pd
Molecular Weight	916.18 g/mol
Synonyms	(S)-BINAP-PdCl2; (S)-(-)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl palladium(II) dichloride; (S)-Tol-BINAP Pd(II) chloride; Pd[(S)-Tol-BINAP]Cl2; (S)-TolBINAP-PdCl2; Palladium(II) chloride complex with (S)-(-)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl; (Sp-4-2)-[(1S)-[1,1'-Binaphthalene]-2,2'-diylbis[bis(4-methylphenyl)phosphine]]dichloropalladium
EINECS	Contact for details

Quality Control

Every batch of our chiral palladium catalyst is synthesized and purified under stringent, inert conditions to prevent decomposition. Quality is assured through comprehensive analytical techniques including NMR, HPLC, and elemental analysis to verify identity, chiral purity (>99% ee), and chemical purity (>98%). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to light and oxygen, this material must be stored under an inert atmosphere (argon or nitrogen) at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Pd Content (ICP-OES)	11.5 - 12.0 %
Solubility	Soluble in dichloromethane, toluene; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.