Description

4-(Tetrahydropyran-4-Yloxy)Benzaldehyde is a high-purity organic building block characterized by its benzaldehyde core functionalized with a tetrahydropyranyloxy group. This compound matters as a versatile and critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials and functional dyes.
• Cross-Coupling Reactions: The aldehyde group is amenable to further functionalization via reactions like Suzuki, Heck, or reductive amination for scaffold diversification.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and asymmetric catalysis within university and CRO laboratories.

Basic Information

Product Name	4-(Tetrahydropyran-4-Yloxy)Benzaldehyde
CAS No.	215460-40-5
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	4-[(Oxan-4-yl)oxy]benzaldehyde; 4-(Tetrahydro-2H-pyran-4-yloxy)benzaldehyde; Benzaldehyde, 4-[(tetrahydro-2H-pyran-4-yl)oxy]-; 4-(Tetrahydropyranyloxy)benzaldehyde; THP-O-Benzaldehyde; 4-(Oxan-4-yloxy)benzaldehyde; 4-(Pyran-4-yloxy)benzaldehyde (tetrahydro); p-(Tetrahydropyran-4-yloxy)benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-(Tetrahydropyran-4-Yloxy)Benzaldehyde is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.