Description

(5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride is a high-purity, halogenated aromatic hydrazine derivative used as a critical building block in advanced organic synthesis. This compound matters because it serves as a versatile precursor for constructing complex heterocyclic scaffolds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bromo-fluoro substitution pattern for enhanced bioactivity.
• Heterocyclic Chemistry: Essential building block for constructing indoles, pyrazoles, and other nitrogen-containing heterocycles via Fischer indole synthesis and related cyclization reactions.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysis, and advanced polymers with specific electronic properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the synthesis of chemical probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules at various scales.

Basic Information

Product Name	(5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride
CAS No.	214916-08-2
Molecular Formula	C6H5BrClFN2
Molecular Weight	239.47 g/mol
Synonyms	5-Bromo-2-fluorophenylhydrazine hydrochloride; (5-Bromo-2-fluorophenyl)hydrazine hydrochloride; 1-(5-Bromo-2-fluorophenyl)hydrazine hydrochloride; 2-Fluoro-5-bromophenylhydrazine hydrochloride; Hydrazine, (5-bromo-2-fluorophenyl)-, hydrochloride; 214916-08-2; 5-Bromo-2-fluoro-phenylhydrazine HCl
EINECS	Contact for details

Quality Control

Our (5-Bromo-2-Fluoro-Phenyl)-Hydrazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.