Description

trans-2-(4-Fluorophenyl)Vinylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing a fluorinated styrene moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from the introduction of the fluorophenylvinyl group.
• Material Science & OLED Development: Serves as a precursor for creating fluorinated organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
• Cross-Coupling Reactions: A versatile reagent specifically for Suzuki-Miyaura cross-coupling with various aryl/vinyl halides to form extended conjugated systems.
• Chemical Biology & Probe Development: Utilized in the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Academic & Contract Research: An essential tool for methodological development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	trans-2-(4-Fluorophenyl)Vinylboronic Acid
CAS No.	214907-24-1
Molecular Formula	C8H8BFO2
Molecular Weight	165.96 g/mol
Synonyms	(E)-2-(4-Fluorophenyl)ethenylboronic Acid; trans-4-Fluorostyrylboronic Acid; (E)-2-(4-Fluorostyryl)boronic Acid; (E)-[2-(4-Fluorophenyl)vinyl]boronic Acid; 2-(4-Fluorophenyl)vinylboronic acid, (E)-; B-(2-(4-Fluorophenyl)vinyl)boronic Acid; 4-Fluoro-trans-styrylboronic Acid; (E)-1-(4-Fluorophenyl)-2-boronoethene
EINECS	Contact for details

Quality Control

Every batch of trans-2-(4-Fluorophenyl)Vinylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, isomeric ratio, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.