Description

7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-(Hydroxymethyl)-, (1R,2S,3S,4S)-Rel- (9Ci) is a high-value, stereochemically defined bicyclic building block used in advanced organic synthesis. This compound is prized for its unique oxanorbornene scaffold and functional handles, which enable the construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring rigid, polycyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides with specific stereochemical requirements.
• Material Science Research: Serves as a precursor for specialty polymers and functional materials with tailored thermal or optical properties.
• Asymmetric Catalysis Ligand Precursor: The defined stereochemistry makes it a valuable starting point for synthesizing novel chiral ligands and organocatalysts.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms or protein interactions due to its reactive aldehyde and hydroxyl groups.
• Academic & Industrial R&D: A versatile building block for methodological development in organic chemistry and total synthesis projects.

Basic Information

Item	Details
Product Name	7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-(Hydroxymethyl)-, (1R,2S,3S,4S)-Rel- (9Ci)
CAS No.	214633-36-0
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	rel-(1R,2S,3S,4S)-3-(Hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; 3-(Hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde, rel-(1R,2S,3S,4S)-; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxaldehyde, 3-(hydroxymethyl)-, (1R,2S,3S,4S)-rel-; Oxanorbornene aldehyde derivative; Chiral oxabicycloheptene aldehyde; Bicyclic ether aldehyde building block
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality management systems to ensure high purity and stereochemical integrity. Our rigorous quality control includes comprehensive analytical characterization using HPLC, GC, NMR, and chiral methods. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric/excess data.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.