Description

3,5,7-Trifluoroadamantane-1-Carboxylic Acid is a highly functionalized, polyfluorinated derivative of adamantane, serving as a sophisticated and versatile building block in advanced organic synthesis. Its unique rigid, cage-like structure combined with strategically placed fluorine atoms makes it invaluable for modulating the physicochemical properties of target molecules, such as lipophilicity, metabolic stability, and membrane permeability. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing novel drug candidates, particularly in central nervous system (CNS) and antiviral research, where the adamantane scaffold and fluorine atoms are pharmacologically advantageous.
• Agrochemical Synthesis: Used in the design and synthesis of new-generation pesticides and herbicides, where its structural properties can enhance biological activity and environmental stability.
• Advanced Material Science: Serves as a precursor for high-performance polymers, liquid crystals, and other specialty materials requiring thermal stability and specific electronic characteristics.
• Fluorine Chemistry Research: An important substrate for studying structure-activity relationships (SAR) and the effects of polyfluorination on organic molecules in academic and industrial R&D settings.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for derivatization into complex ligands for catalysis or molecular recognition applications.

Basic Information

Product Name	3,5,7-Trifluoroadamantane-1-Carboxylic Acid
CAS No.	214557-89-8
Molecular Formula	C11H13F3O2
Molecular Weight	234.22 g/mol
Synonyms	1-Adamantanecarboxylic acid, 3,5,7-trifluoro-; 3,5,7-Trifluoroadamantane-1-carboxylic acid; 1-Carboxy-3,5,7-trifluoroadamantane; Trifluoroadamantanecarboxylic acid; Adamantane-1-carboxylic acid, 3,5,7-trifluoro derivative; F3-Adm-COOH
EINECS	Contact for details

Quality Control

Every batch of 3,5,7-Trifluoroadamantane-1-Carboxylic Acid is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.