Description

3,5,7-Trifluoroadamantane-1-Carboxylic Acid Methyl Ester is a highly functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique, rigid polycyclic cage structure, combined with strategically placed fluorine atoms, makes it invaluable for modulating the physicochemical properties of target molecules. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research, where the adamantane core is pharmacologically privileged.
• Agrochemical Development: Used in creating advanced pesticides and herbicides, where the fluorine atoms enhance lipophilicity, metabolic stability, and membrane permeability.
• Material Science Precursor: Serves as a monomer or cross-linking agent for synthesizing specialty polymers with enhanced thermal stability, chemical resistance, and unique dielectric properties.
• Ligand and Catalyst Design: The ester and fluorine functionalities make it a useful precursor for designing novel ligands in asymmetric catalysis and organometallic chemistry.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) and the effects of polyfluorination on a rigid three-dimensional scaffold.
• High-Performance Liquid Chromatography (HPLC) Standard: Can be utilized as a reference standard or marker in analytical method development due to its distinct chemical structure.

Basic Information

Product Name	3,5,7-Trifluoroadamantane-1-Carboxylic Acid Methyl Ester
CAS No.	214557-84-3
Molecular Formula	C12H15F3O2
Molecular Weight	248.24 g/mol
Synonyms	Methyl 3,5,7-Trifluoroadamantane-1-carboxylate; 1-Carbomethoxy-3,5,7-trifluoroadamantane; 3,5,7-Trifluorotricyclo[3.3.1.13,7]decane-1-carboxylic Acid Methyl Ester; Trifluoroadamantane-1-methylcarboxylate; Adamantane, 3,5,7-trifluoro-1-(methoxycarbonyl)-; Methyl 3,5,7-trifluorotricyclo[3.3.1.13,7]decane-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3,5,7-Trifluoroadamantane-1-Carboxylic Acid Methyl Ester is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.