Description

Thiazole-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of novel drug candidates, particularly those containing thiazole and biaryl motifs.
• Agrochemical Synthesis: Used in creating advanced fungicides, herbicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Catalyst & Ligand Development: Serves as a precursor for novel catalysts and ligands in transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	Thiazole-2-Boronic Acid Pinacol Ester
CAS No.	214360-88-0
Molecular Formula	C11H16BNO2S
Molecular Weight	237.13 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; Thiazol-2-ylboronic Acid Pinacol Ester; 2-Thiazoleboronic Acid Pinacol Ester; 2-(Thiazol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol Thiazole-2-boronate; 2-Borono-thiazole Pinacol Ester; 2-Thienylboronic Acid Pinacol Ester (common misnomer, related class)
EINECS	Contact for details

Quality Control

Our Thiazole-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.