Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a protected phenol boronic acid, enabling efficient cross-coupling reactions under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require phenol-boronate functional groups.
• Liquid Crystal & OLED Materials: Building block for creating organic semiconductors, light-emitting diodes (OLEDs), and liquid crystal display (LCD) components.
• Polymer & Resin Modification: Enables the functionalization of polymers and epoxy resins to impart specific thermal or chemical properties.
• Organic Synthesis & Catalysis: A valuable reagent in academic and industrial R&D for constructing biaryl and heterobiaryl structures common in natural products and catalysts.
• Sensor Development: Used in the fabrication of chemical sensors and probes due to its boronate group's affinity for diols and other analytes.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	214360-76-6
Molecular Formula	C12H17BO3
Molecular Weight	220.07 g/mol
Synonyms	3-Hydroxyphenylboronic acid pinacol ester; 3-Phenolboronic acid pinacol ester; (3-Hydroxyphenyl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenol; 3-Boronophenol pinacol ester; Pinacol 3-Hydroxyphenylboronate; 3-(Pinacolatoboryl)phenol; B-(3-Hydroxyphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards required for cGMP and ISO-guided manufacturing environments, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.