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(3-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester CAS NO 214360-75-5


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CAS No.:214360-75-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds under mild conditions. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for constructing complex molecular architectures in drug discovery and advanced material synthesis.

Application

  • Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
  • Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for palladium-catalyzed coupling with aryl/vinyl halides to create biaryl structures.
  • Material Science Research: Used in the development of organic electronic materials, such as OLEDs and conductive polymers, where specific aryl linkages are required.
  • Agrochemical Synthesis: Employed in the research and production of advanced herbicides and fungicides that contain complex aromatic systems.
  • Ligand and Catalyst Development: Acts as a precursor for creating novel bidentate ligands and organometallic catalysts.
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Item Details
Product Name (3-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester
CAS No. 214360-75-5
Molecular Formula C21H22BNO4
Molecular Weight 363.22 g/mol
Synonyms 3-(Phthalimidomethyl)phenylboronic acid pinacol ester; 3-Phthalimidomethylbenzeneboronic acid pinacol ester; (3-(Phthalimidomethyl)phenyl)boronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[3-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]-4,4,5,5-tetramethyl-; Boronic acid, B-[3-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]-, 1,1-dimethylethyl ester; Pinacol (3-phthalimidomethylphenyl)boronate
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Quality Control

Our (3-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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