Description

(3-Bromomethylphenyl)Boronic Acid Pinacol Ester is a high-purity organoboron building block, specifically a protected boronic acid derivative. This compound is critical for enabling efficient and selective Suzuki-Miyaura cross-coupling reactions in complex molecule synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing biaryl and conjugated systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biphenyl structures.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise conjugation is essential.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	(3-Bromomethylphenyl)Boronic Acid Pinacol Ester
CAS No.	214360-74-4
Molecular Formula	C₁₃H₁₈BBrO₂
Molecular Weight	297.00 g/mol
Synonyms	3-(Bromomethyl)phenylboronic acid pinacol ester; (3-(Bromomethyl)phenyl)boronic acid pinacol ester; 2-(3-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Bromomethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 3-Bromomethylbenzeneboronic acid pinacol ester; m-(Bromomethyl)phenylboronic acid pinacol ester; Boronic acid, B-[3-(bromomethyl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (3-Bromomethylphenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.